Thursday 29 November 2018

Genetic Counseling and Testing for Colorectal Cancer in Young Adults: Mini-Review: (PRJFGS) - Lupine Publishers




Colorectal cancer (CRC) has one of the largest proportions of familial cases. Two to 5% of all colon cancers arise in the setting of inherited syndromes, including Lynch syndrome (hereditary nonpolyposis colorectal cancer [HNPCC]), familial adenomatous polyposis (FAP), attenuated FAP, MUTYH-associated polyposis (MAP), and certain hamartomatous polyposis conditions like Peutz-Jeghers syndrome (PJS) and juvenile polyposis syndrome (JPS). All of these conditions are inherited, autosomal dominant disorders, except MAP, which is autosomal recessive [l]. Although clinical similarities do exist, each has different cancer risks, characteristic clinical features, and separate genetical etiologies. In addition to these syndromes, up to 30 % of colon cancers exhibit increased familial risk, likely related to inheritance. A number of less penetrant, but possibly more frequent susceptibility genes have been identified for this level of inheritance. 

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Monday 26 November 2018

Pitfalls in the Genetic Identification of Human Remains: (PRJFGS)- Lupine Publishers



DNAtechnology is an irreplaceable tool for the identification of human remains, but the reliability of the ante mortem reference data remains a serious concern. We present here two cases where misleading conclusions could be achieved by using only the genetic profile of the missing person's father such as reference sample. Nevertheless, when appropriate reference DNA samples (e.g., the maternal samples) became available, certain identifications were achieved as shown by the probability of maternity (> 99.999%). Thus, all these data together show that extra-pair paternity was found by the way, in both cases. Precautions to avoid misleading conclusions are addressed.

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Thursday 22 November 2018

Forensic Nanotechnology in Forensic Genetics: (PRJFGS)- Lupine Publishers


Forensic Nanotechnology in Forensic Genetics by  Anand Lodha in Peer Reviewed Journal of Forensic & Genetic Sciences (PRJFGS) in Lupine Publishers

DeoxyriboseNucleic Acid (DNA) is unique to each and every individual and it remains constant throughout the life as it follows the laws of Mendelian inheritance. However DNA analysis is widely accepted techniques for personal identification. DNA extraction and isolation from ancient bone samples, degraded body parts etc. is still quite difficult and challenging task for forensic scientist. But new upcoming technology like nanotechnology will help for analysis of such samples for DNA. Hence, in this review article we are short listed some of the research articles which used the different nanoparticles for DNA extraction. Where different nanoparticles used for the DNA extraction were cited and explained in brief.

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Monday 19 November 2018

The Case of the Fraudulent “Free Gift”- Amazon.Com and Luminary Skin Care: (PRJFGS)- Lupinne Publishers


The Case of the Fraudulent “Free Gift”- Amazon.Com and Luminary Skin Care by Cam Caldwell in Peer Reviewed Journal of Forensic & Genetic Sciences (PRJFGS) in Lupine Publishers


One of the realities of human psychology is that people want "something for nothing” [1]. Franklin P. Jones, the long-time humorist whose column in the Saturday Evening Post was its longest continually posted feature, once wisely observed, "If you get something for nothing, you just haven't been billed yet [2]. "Jones was only partially right in today's credit card age when some fraudulent advertisers access your credit card balance without even the courtesy of a bill before the fact! Unfortunately, one of the more disappointing realities of business life is that the name of the highly regarded Amazon.com corporation-one of America's most highly respected companies [3] has been used to perpetuate a fraud by Luminary Skin Care, yet Amazon.com is allowing this fraud to go on unchecked.



Tuesday 13 November 2018

Enforcement of Regulatory Bodies to Trade Indian Medicinal Plants and DNA Bar-coding In Wildlife Forensics: (PRJFGS) - Lupine Publishers



India's diverse topology and habitat flourishes near about 45,000 species of plants. Certain species among these plants are medicinal plant species which are endemic to India. These plants are valuable for their medicinal or aromatic properties. Due to India's biodiversity abundance, plants from the wild are wildly exploited resulting in over exploitation of medicinal plants. The present review is carried out to ascertain the rules and their regulations in various states of India which are presently saving the national heritage and helping officials to apprehend herb smugglers. The review also presents the data suggesting the present scenario of advancements in the field of wild life forensic genetics to deal with such cases and technical advancements in the field of plant/part identification during the confiscations in various states.



Thursday 8 November 2018

The Aging Process and Time: (PRJFGS)- Lupine publishers

Critical Analysis of the Definition of the Meter: (PRJFGS)- Lupine Publishers

Flaky Academic Journals: Lupine Publishers "craves to select scientific con...

Flaky Academic Journals: Lupine Publishers "craves to select scientific con... : Lupine Publishers describes itself (on its website, 2/...